Regulatory

Part:BBa_K3506000

Designed by: Xinmiao Li   Group: iGEM20_BNU-China   (2020-10-21)


A sequence of the first 124 amino acids of Cyclin B2

Over the four mitotic cyclins, cyclin b2 has the most important role in the yeast Saccharomyces cerevisiae, which is sufficient to trigger all essential functions of cyclin-dependent kinases in mitosis by itself. Research shows that a Clb2 KEN box can only degrade targeted fusion protein with the help of the first 124 amino acids of Clb2. So during MA and G1, a sequence of Clb2 124aa containing the KEN box and the destruction box act together to regulate proteolysis of Clb2 fusion protein.[1]

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None